Quantitative analysis of choroidal alterations in thyroid eye disease using swept-source OCT

نویسندگان

چکیده

Purpose: To investigate choroidal alterations in patients with thyroid eye disease (TED) using swept-source optical coherence tomography (SS-OCT) and compare them age-matched healthy controls. Methods: SS-OCT scans were performed to obtain quantitative measurements of parameters. Mean thickness (MCT), vessel volume (CVV), stroma (CSV), vascularity index (CVI), stroma-to-vessel ratio (CSVR) calculated compared between TED control eyes. Results: eyes exhibited significantly higher MCT (276.25 ± 58.75 μm vs . 236.86 45.02 μm, p < 0.001), CVV (21.46 5.10 mm 3 18.14 3.83 , = CSV (13.86 2.80 11.44 2.17 0.001) However, there no significant differences CVI (0.61 0.02 0.61 0.03, 0.838) or CSVR (0.65 0.05 0.64 0.07, 0.345) the two groups. Conclusion: effectively differentiated from normal based on alterations. The increased MCT, CVV, suggest both dilated vasculature expanded stroma. These findings highlight potential as an adjunctive imaging tool for assessment TED.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Choroidal Thickness in 3001 Chinese Children Aged 6 to 19 Years Using Swept-Source OCT

The purpose of the cross-sectional study is to describe the values and distribution of choroidal thickness and to explore its related factors, especially age, in Chinese children. A total of 3001 Chinese school children aged 6 to 19 years underwent comprehensive ophthalmic examinations, including axial length and cycloplegic refraction. Choroidal thickness was measured by swept-source optical c...

متن کامل

Comparison of choroidal thickness measurements between spectral-domain OCT and swept-source OCT in normal and diseased eyes

PURPOSE Sub-foveal choroidal thickness (SFCT) is affected in many ocular diseases. The aim of this study was to compare SFCT measurements between Topcon 3D 2000 spectral-domain optical coherence tomography (SD-OCT) and Topcon swept-source OCT (SS-OCT), with different laser wavelengths, in normal and diseased populations. MATERIALS AND METHODS This was a prospective, cross-sectional, noninterv...

متن کامل

Automated Quantitation of Choroidal Neovascularization: A Comparison Study Between Spectral-Domain and Swept-Source OCT Angiograms

Purpose To compare the lesion sizes of choroidal neovascularization (CNV) imaged with spectral-domain (SD) and swept-source (SS) optical coherence tomography angiography (OCTA) and measured using an automated detection algorithm. Methods Patients diagnosed with CNV were imaged by SD-OCTA and SS-OCTA systems using 3 × 3-mm and 6 × 6-mm scans. The complex optical microangiography (OMAGC) algori...

متن کامل

In vivo imaging of the rodent eye with swept source/Fourier domain OCT

Swept source/Fourier domain OCT is demonstrated for in vivo imaging of the rodent eye. Using commercial swept laser technology, we developed a prototype OCT imaging system for small animal ocular imaging operating in the 1050 nm wavelength range at an axial scan rate of 100 kHz with ~6 µm axial resolution. The high imaging speed enables volumetric imaging with high axial scan densities, measuri...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Frontiers in Physics

سال: 2023

ISSN: ['2296-424X']

DOI: https://doi.org/10.3389/fphy.2023.1240728